Apoptosis Reagents and Kits
Enzo Life Sciences Apoptosis Activator 2 (5mg). CAS: 79183-19-0
Induces apoptosis by promoting the oligomerization of Apaf-1 into the mature, functional apoptosome, triggering caspase-9 activation resulting in activated caspase-3. Shows strong selectivity for cancer cells against normal cell lines. Acts in a similar way like apoptosis inducer PETCM (ALX-420-031). Alternative name: 1-[(3,4-Dichlorophenyl)methyl]-1H-indole-2,3-dione. Purity: ≥98% (HPLC). Appearance: Orange to red solid. Solubility: Soluble in DMSO (5mg/ml), methanol (5mg/ml) or 100% ethanol. Long Term Storage: +4°C.
Enzo Life Sciences BAFF-R (human) : Fc (human), (recombinant) (50µg)
Alternative name: TNFRSF 13C, BR3, BlySR3, CD268. Concentration: 1mg/ml (after reconstitution). Purity: ≥95% (SDS-PAGE). Formulation: Lyophilized. Contains PBS. Source: Produced in HEK 293 cells. The extracellular domain of human BAFF-R (aa 2-71) is fused at the C-terminus to the Fc portion of human IgG1. Specificity: Binds human and mouse BAFF. Long Term Storage: -20°C. Applications: ELISA .
Enzo Life Sciences NUCLEAR-ID Green chromatin condensation detection kit (1Kit)
The NUCLEAR-ID Green Chromatin Condensation Detection Kit detects nuclear condensation using a DNA intercalating dye that brightly stains the condensed chromatin of apoptotic cells, but only dimly stains the uncondensed chromatin of healthy living cells. Mechanism of Action The cell-permeable dye used in this application is an aromatic, planar cationic structure that inserts between stacked base pairs on the DNA duplex, providing an environmentally-dependent fluorescence enhancement of the dye molecules and large increases in fluorescence signal relative to the free dye in solution. Since the signal enhancement provides a proportional response, direct quantitation of DNA is possible. Further signal increase is observed upon DNA condensation during apoptosis.Applications: Flow Cytometry, Fluorescence microscopy, Fluorescent detection .
Biotium Apoptosis Assays Fluorescent Proteins Nucleotides Other Conjugates Annexin V Conjugates CF740 1/EA
Annexin V fluorescent conjugates can be used to detect apoptotic cells The human anticoagulant Annexin V is a 35-36 kDa calcium-dependent phospholipid-binding protein with high affinity for phosphatidylserine (PS) This product is labeled with near-infrared CF740 Dye (Ex/Em 742/762 nm)
Abcam Mouse IL-19 Antibody Pair - BSA and Azide free, 10 x 96 Tests
Mouse IL-19 Antibody Pair - BSA and Azide free is a kit containing recombinant capture and detector antibodies in a carrier-free formulation for the measurement of Mouse IL-19.
The product is subject to the following: Abcam Restricted Use Statement
Enzo Life Sciences Z-WEHD-FMK (Ready-to-Use) (100µl)
Irreversible, cell permeable inhibitor of caspase-1 and -5. Inhibits also caspase-4 and-14. Designed as a methyl ester to facilitate cell permeability. Alternative name: Caspase 1 inhibitor (fluoromethylketone), Caspase 5 inhibitor (fluoromethylketone). Formula: C37H42FN7O11. MW: 763.8. Purity: ≥99% (HPLC). Formulation: Liquid. In DMSO. Long Term Storage: -20°C.
STEMCELL Technologies Annexin V, PE, Size: 25 Tests
Annexin V is a member of the annexin family of proteins that bind to membrane phospholipids in the presence of calcium. This dye has high affinity for phosphatidylserine (PS) that is present in the inner leaflet of the plasma membrane. Verified for use with flow cytometry assays use this antibody to detect the translocation of PS to the external environment. Annexin V is used along with viability dyes such as 7-AAD (Catalog 75001) or Propidium Iodide (Catalog 75002). The process of PS translocation occurs prior to the loss of membrane integrity. Therefore as cells progress through apoptosis and towards necrosis the cell membrane is compromised and consequently viability dyes pass into the cell. Thus cells undergoing early apoptosis stain positive for Annexin V and negative for viability dyes while apoptotic death or necrosis is characterized by positive staining for both Annexin V and the viability d
Meso Scale Discovery R-PLEX Human Caspase-1 ASYQP
The R-Plex Human Caspase-1 Assay Kit from Meso Scale Discovery is used to quantitatively measure caspase-1 in human biological samples such as serum plasma cell culture supernatants and cell lysates The assay uses electrochemiluminescence (ECL) detection technology and provides high sensitivity a broad dynamic range and requires low sample volume The kit includes a 96-well plate coated with capture antibodies detection antibodies labeled with an ECL tag and calibrator diluent The assay takes approximately 3 5 hours to complete after a 2 hour incubation period The kit can perform up to 94 assays in the 96-well plate format
Enzo Life Sciences Apoptosis Activator 2 (25mg). CAS: 79183-19-0
Induces apoptosis by promoting the oligomerization of Apaf-1 into the mature, functional apoptosome, triggering caspase-9 activation resulting in activated caspase-3. Shows strong selectivity for cancer cells against normal cell lines. Acts in a similar way like apoptosis inducer PETCM (ALX-420-031). Alternative name: 1-[(3,4-Dichlorophenyl)methyl]-1H-indole-2,3-dione. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO (5mg/ml), methanol (5mg/ml) or 100% ethanol. Long Term Storage: +4°C.
Cayman Chemical Ac-AAVAlPAVlAlAP-VAD-CHO 500ug
A composite of a non-selective caspase inhibitor and a cell-permeable hydrophobic sequence; a non-selective caspase inhibitor
Enzo Life Sciences SUPERFASLIGAND Protein (soluble) (human), (recombinant) (5µg)
SUPERFASLIGAND (soluble) (human), (recombinant) features an N-terminus linker shown to improve stability and enhance immune activation compared to recombinant ligands alone. SUPERFASLIGAND (soluble) (human), (recombinant) features an N-terminus linker shown to improve stability and enhance immune activation compared to recombinant ligands alone. Alternative name: FasL (oligomer), APO-1L (oligomer), CD95L (oligomer), CD178 (oligomer), TNFSF 6 (oligomer). Concentration: 0.1mg/ml after reconstitution. Purity: ≥95% (SDS-PAGE). Formulation: Lyophilized. Contains PBS. Source: Produced in HEK 293 cells. The extracellular domain of human FasL (APO-1L; CD95L; CD178) (aa 103-281) is fused at the N-terminus to a linker peptide (26 aa) and a FLAG-tag. Glycosylation of rhs SUPERFASLIGAND is similar to natural human FasL. Specificity: Binds to human, mouse and rat Fas (CD95; APO-1). Long Term Storage: -20°C. Applications: ELISA .
Cytek Biosciences Inc Annexin V Binding Buffer (1X)
Annexin V Binding Buffer (1X) ..... Cat. No. TNB-5000-L050 ..... Size 50 mL